2026-09-17 10:55:36   中国药房 2026年37卷第11期采用网络药理学和生物信息学分析并预测虫草素延缓AKI-CKD的信号通路及其与铁死亡途径的关系。采用细胞实验对预测结果进行验证：将人肾小管上皮细胞HK-2分为空白组、虫草素组、模型组、H2O2+虫草素组，除空白组和虫草素组外，其余各组加入150 μmol/L H2O2处理72 h以诱导细胞持续性氧化应激损伤；虫草素（40 μmol/L）干预72 h后，检测细胞中谷胱甘肽过氧化物酶4（GPX4）...

2026-09-16 11:40:47   UMD News / PNAS | 2026-07-01马里兰大学St.Leger团队发现，绿僵菌（M. robertsii）代谢广度越广，杀虫越快、植物根系定殖越强，破解"杀虫vs共生"权衡之谜，发表于《PNAS》(2026.07.01)。...

2026-09-16 11:19:57   探微者真菌三剑客到今天凑齐了——第16期木霉打真菌，第17期淡紫拟青霉打线虫，这期收官：昆虫病原真菌（绿僵菌 Metarhizium 和白僵菌 Beauveria）打虫子。它们用的是同一种武器——附着胞（appressorium），但产生的破坏力来自一个你意想不到的物理原理：甘油渗透压。Trends in Microbiology 2024年发了一篇来自中科院的综述，把绿僵菌和白僵菌并排拆开了感染昆虫...

2026-09-16 10:41:33   科学报告 | (2022) 12:5853本研究通过单因素实验、均匀设计和非线性回归分析，优化了蝉拟青霉（Paecilomyces cicadae）产麦角甾醇过氧化物（EP）的培养基组分。优化后EP产量达256 μg/L，较未优化前提高5倍。通过建立Monod模型、Andrews模型、Contois模型和Aibe模型，分析了发酵液黏度、底物及产物对菌体生长的影响。结果表明：Monod模型能较好预测菌体生长；黏度与底物对EP浓度的影响显著...

2026-09-16 10:05:16   Scientific Reports | (2022) 12:5853we optimized medium components for the production of ergosterol peroxide (EP) by Paecilomyces cicadae based on a mono-factor experiment, a uniform design, and a non-linear regression analysis....

2026-09-16 09:23:11   Scientific Reports | (2022) 12:5853we optimized medium components for the production of ergosterol peroxide (EP) by Paecilomyces cicadae based on a mono-factor experiment, a uniform design, and a non-linear regression analysis....

2026-09-14 17:16:10   Frontiers in Microbiology 03 August 2026With the rising prevalence of vector-borne diseases and insecticide resistance in mosquitoes, alternative vector control strategies are urgently needed. Fungal entomopathogens offer a promising...

2026-09-14 15:24:44   Frontiers in Microbiology 03 August 2026With the rising prevalence of vector-borne diseases and insecticide resistance in mosquitoes, alternative vector control strategies are urgently needed. Fungal entomopathogens offer a promising...

2026-09-14 15:00:55   Frontiers in Microbiology 03 August 2026With the rising prevalence of vector-borne diseases and insecticide resistance in mosquitoes, alternative vector control strategies are urgently needed. Fungal entomopathogens offer a promising...

2026-09-14 11:27:33   Frontiers in Microbiology 03 August 2026With the rising prevalence of vector-borne diseases and insecticide resistance in mosquitoes, alternative vector control strategies are urgently needed. Fungal entomopathogens offer a promising...